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2020-09-23 15:52:04'You can't pull a highly effective drug out of a cylinder like a bunny without side effects,' John's father always said. John stuck to this motto because he knew only too well that the problems and pitfalls lay in the details.
Although John could not pay his research team the hefty corporate fees, he had created a working atmosphere that was pleasant and constructive for his employees. They had no idea of the pressure that Philipp was exerting and that John was absorbing.
One of his particularly top employees was Alex Sommer. Alex was not only an excellent chemist, but also a friend and confidante of John.
The two men had been fellow students at the same university. But after graduating, the two lost sight of each other. John had stayed in Canada while Alex accepted a job offer in Washington. By chance the two met again in New York at a congress for stem cell research.
Alex had told John about the sometimes untenable conditions in his company, which made it difficult to work constructively. John had seized the opportunity to win Alex over to the company. In Alex Schlepptau, a second, highly qualified physicist left the group to join Lombard Pharma.
After taking over the business from their late father, the brothers realized that they would not be able to withstand the strong competitive pressure in the long run.
Too many suppliers with products that were too good sprang up like mushrooms that made the pieces of the cake narrower and narrower.
In order not to fall by the wayside, new paths had to be found. Lombard Pharma wanted to create a second mainstay, so research into a drug against obesity began more than three years ago.
An alarming study had indicated that an average of 2.5 kilos had been gained since the 1970s. The problem of obesity has grown rapidly in the United States in particular.
More than 5% of the population suffers from extreme obesity and 20% of all Americans are overweight, with the result that diabetes, heart problems, high blood pressure, gallstones or cancer have increased dramatically.
Now John's research department was on the cusp of untying this Gordian knot. A pill should get rid of excess pounds. The active ingredient rimonabant suppresses the craving for delicacies and, as a positive side effect, also curbs the addiction to cigarettes.
The drug tested extremely positive in rats and guinea pigs. However, certain substances in it increase the serotonin levels in the brain. If the drug is administered over a long period of time, it will damage the heart valves.
In addition, increased pressure of the pulmonary arteries, hyperthyroidism and kidney dysfunction were diagnosed. Although they tried to reduce these side effects as much as possible, they were not yet able to eliminate them completely or to bring them into an area that was harmless.
For these reasons, the drug remained in the test phase.
This miracle pill also sparked the argument between the two brothers. Philipp urged John to finally release the drug. Almost all pharmaceutical companies are working on such a slimmer.
In view of the high profit prospects with the slim line, work was done at full speed to regulate the food cravings of the oversaturated society.
Under all circumstances, Philipp wanted to be one of the first to bring a weight-reducing drug onto the market.
Because if he really succeeded in this, then he would finally have the magic key that would open all doors and gates in business and society for him. Nobody could then stop him from expanding and realizing his dream of expanding the company into a group with global branches.
However, the situation came to a head six months ago that there was a tangible dispute at the General Assembly in April. Philipp had tacitly obtained the test reports and evaluations from the research laboratory. At first glance, John knew it was Alex Summer's notes.
His friend suffered from the quirk that he did not write the test reports straight away on the PC, but wrote them by hand beforehand, because that way he would remember everything better, as he claimed.
And now John had seen the copy of the handwritten papers on the conference table. How Philip had come up with these files had been a mystery to John. Absolutely nothing was allowed to leave the research department without his consent. However, John had been convinced that Alex had not voluntarily given the documents to Philipp.
From this report it emerged that the side effects of the drug had been reduced to such an extent that it could already be administered to test subjects. With this statement, Philipp had taken the members of the council by surprise.
Because at the last autumn meeting, John had announced that the test phase of RNV3 on humans would come into question at the earliest in one, but at the latest in two years.
John hadn't expected that Philipp would take him off guard at the general assembly. Because the way Philipp had presented the situation, it seemed as if RNV3 was just OK. the shareholder would have needed to be administered to test subjects.
The euphoria in Summers' report had been obvious, since, according to him, the new tests on two rhesus monkeys had proven to be extremely positive, because the side effects had been absolutely limited. The setback had only come a day before the meeting. The male monkey had died of heart failure the night before last.
For his part, John had now submitted the full report and strongly advised against giving consent to pass RNV3 on to test subjects.
The drug is still too half-baked to endanger human life with it. This setback had thrown research back months, maybe even years. The Sisyphean work started all over again, to re-dose the active ingredients or to find replacements for certain life-threatening substances.
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The Clever Girl Detroyed hopes
The general assembly then went completely different from the way Philipp had imagined. The unexpected setback that the monkey died in the test phase just before the shareholders' meeting destroyed all of his hopes. Now there was no way to escape the Mafia's stranglehold. If he wanted to stay alive, he had to do whatever they asked of him. And Pamela didn't hold back long after the change was due.As an enterprising woman, Pamela knew exactly what she wanted. It was also in their interest that RNV3 should go into production as soon as possible. So Pamela had hatched a diabolical plan that lived up to her evil character.After the terrible scandal during the general assembly, the time was extremely favorable to take Philipp out of the company and send him to a diving station. Due to Philip's sudden failure, as sole managing director, John should quickly have got into trouble to continue the company profitably. Pamela had expected a rapid decline in business, so that John w
The Clever Girl The study
In the course of the next few weeks, Philipp had more and more trust in Pamela. He told her about the problems in the company, the study that was commissioned, and the vast sums of money the research devoured. In this context, he had also told her about the problems with his brother and that he had no idea how difficult it was to raise this money, when the company was nowhere near as much as the research was currently devouring. And investors were in short supply anyway. In addition, the banks did not want to grant any more credit increases. On the contrary, they were even considering calling the loans due if the necessary progress was not made soon.Without being aware of it, he had given Pamela exactly the information she wanted. Pamela had made it appear as if she wanted to help Philipp out of a tight spot and offered him a change in the amount of the loan amount to cover the loan. Seen in this way, he would have been creditworthy again and more time could have been given t
The Clever Girl Other woman
Philipp had deliberately dropped into the snow and was waiting. He could still take out the radio and warn John. Or he simply failed to raise his ski pole and wave that the signal for the two explosives experts was to detonate the dynamite to set off the murderous avalanche.The two men had already been looking for the right places yesterday where the greatest possible exit was guaranteed.They now lurked hidden behind a protruding rock and watched Philip with hawk eyes. Philipp had no choice, he had to sacrifice his brother for his own life. With incredible effort, he raised his stick and waved it. Immediately afterwards the earth began to shake and a tremendous thunder and rumble filled the mountains.A huge slab of snow had come loose and was moving at high speed straight towards John. But John reacted immediately and drove rapidly down the mountain. Philipp watched John's shot drive tense. Without realizing that he was screaming, he cheered on his brother vi
The Clever Girl Last prayer
“Do you think that it really makes sense to do the descent in this weather?”“You don't need to worry. According to the last weather report, the weather remains stable. The pilot also confirmed to me that it would not start to snow, "said Philipp soothingly.“There should be great powder snow in the upper half of the descent. The route is new and only opened up last year. It leads through a wonderful area. I hope you are rested and in good shape, because this descent is really only for experts. ”John nodded confidently, although he wasn't really sure whether he would be fit today. But he didn't want to show himself naked in front of Philip and appear weak."Who else is there?" Asked John."Nobody, just you and me.""Isn't it a little dangerous when only the two of us are on the road?""Come on, where is your sense of adventure?" Replied Philipp challengingly. "We're not wimps, we're real men," he continued euphorically and patted John encou
The Clever Girl Weather
A week ago, Philipp had called John and told him that he was ready to return to the company. Philipp would now have had enough time to think about how things should go on for him. But he didn't want to talk to John about this delicate matter in the company, but on neutral ground, where there was a relaxed atmosphere and where neither would be exposed to stress or distraction from the company.For this reason Philipp invited his brother to go skiing in Jasper this weekend. Both were excellent skiers, one of the few things they shared in common. The snowfall had started quite early this year, so the conditions for helicopter skiing were just ideal.Even though John didn't actually have time to ski, there was no way he wanted to turn down Philip's request.He urgently needed Philipp in the company so that he could finally concentrate on research again. Perhaps it was really good that he had a physical distance from the pending problems of the company. In the past f
The Clever Girl Research work
The shareholders had considered John's concerns to be justified and decided against trying the drug on people. The side effects had to be reduced to such an extent that there was no danger to life and permanent damage was also excluded.After the session ended, a heated argument broke out between the two brothers. John had thrown Philipp's incompetence and greed for profit at the expense of others, while Philipp had described his brother as a coward, procrastinator and fearful rabbit, whose willingness to take risks was zero. Philipp was fed up with being put off all the time, while other companies were a lot further with the development of the drug. He wanted to finally get results and not just watch as vast amounts of company money were pumped into research that was unable to finally develop an efficient drug.Here he had met John at a sore point, because he was only too aware of how much money this project cost and how much his meticulous work was thrown back again an
